Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418239 | 1.00 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL14762028 | 0.97 | LMNA (0.33) | LMNA | |
| SCHEMBL8672889 | 0.91 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL29743191 | 0.90 | LMNA (0.30) | LMNA | |
| SCHEMBL1687045 | 0.88 | LMNA (0.32) | LMNA | |
| SCHEMBL7773758 | 0.85 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL3629754 | 0.85 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL1526904 | 0.85 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL3626391 | 0.85 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL5165029 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212053-B2 | Process for preparing heteroaromatic ring compound having N-Rf group | DAIKIN INDUSTRIES, LTD. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20100222598-A1 | PROCESS FOR PREPARING HETEROAROMATIC RING COMPOUND HAVING N-Rf GROUP | DAIKIN INDUSTRIES, LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222598-A1 | PROCESS FOR PREPARING HETEROAROMATIC RING COMPOUND HAVING N-Rf GROUP | CYP2F1, AFF1, AFF2 | LMNA 1919/4885THRB 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.