Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9294951 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL9295429 | 0.81 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CALDH1A1KMT2A | |
| SCHEMBL563350 | 0.80 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL30865655 | 0.78 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL9295322 | 0.78 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL9294956 | 0.77 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CF2RL3TP53 | |
| SCHEMBL14231749 | 0.76 | MAOB (0.59) | ALDH1A1MAOBKMT2ANPC1RAB9A | |
| SCHEMBL10902022 | 0.74 | RAB9A (0.50) | MAOBKMT2ANPC1RAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9327988 | 0.72 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CALDH1A1KMT2A | |
| SCHEMBL3978200 | 0.70 | MAOB (0.64) | ALDH1A1MAOBKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946259-B2 | Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors | HIGH POINT PHARMACEUTICALS, LLC (US) | 2015-02-03 | — | — | US | disclosed |