SCHEMBL16420323

SCHEMBL16420323

Cc1cc(N2c3ccccc3N(C)[C@H]2C)c(C)c(N2c3ccccc3N(C)[C@@H]2C)c1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ PDGFRB P09619 1/20 0.36
▸ PTPN2 P17706 1/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ GPR3 P46089 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ HTT P42858 1/20 0.33
▸ TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16420314 0.92 KDM4E (0.35) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL17131424 0.92 KDM4E (0.35) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL24596461 0.91 KDM4E (0.37) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16420322 0.89 KDM4E (0.47) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16420354 0.85 PTPN2 (0.31) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16424290 0.85 KDM4E (0.31) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16709188 0.84 HSD17B10 (0.39) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16420349 0.84 KDM4E (0.41) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL17655184 0.84 HSD17B10 (0.39) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL16769708 0.82 ALDH1A1 (0.42) KDM4EALDH1A1GAAHPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10930866-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-23 — — US disclosed
US-20200176694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20170250354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-08-31 — — US disclosed
US-9748504-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-29 — — US disclosed
US-20150280146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-01 — — US disclosed
US-20150028290-A1 HETEROLEPTIC OSMIUM COMPLEX AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10930866-B2 Organic electroluminescent materials and devices OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885
US-20150280146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, SSB, RO60 KDM4E 2698/4885ALDH1A1 2401/4885GAA 3572/4885
US-20200176694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885
US-20170250354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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