Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170788 | 0.96 | — | — | |
| Nitrogen SCHEMBL28826445 | 0.90 | TSHR (0.53) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| Ethylene SCHEMBL28314914 | 0.90 | TSHR (0.53) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| SCHEMBL147796 | 0.89 | — | — | |
| SCHEMBL28097444 | 0.86 | TSHR (0.47) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| Bromide SCHEMBL30994910 | 0.86 | TSHR (0.47) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| SCHEMBL13538918 | 0.84 | TSHR (0.47) | TSHRRAPGEF4CYP3A4TP53SMN1; SMN2 | |
| SCHEMBL788179 | 0.82 | TSHR (0.44) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| SCHEMBL5424151 | 0.78 | ALDH1A1 (0.43) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 | |
| SCHEMBL27856299 | 0.78 | TSHR (0.39) | TSHRRAPGEF4CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286591-B | Synthesis method of drug Tafamidis | 湖南第一师范学院 | 2023-10-20 | — | — | CN | claimed |
| CN-115286591-A | Synthetic method of drug Tafamidis | 湖南第一师范学院 | 2022-11-04 | — | — | CN | claimed |
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | TSHR 3229/4885RAPGEF4 3267/4885CYP3A4 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.