SCHEMBL170788

SCHEMBL170788

Cc1cc(Cl)cc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1642052 0.96 TSHR (0.57)
Nitrogen SCHEMBL28826445 0.93 TSHR (0.53)
Ethylene SCHEMBL28314914 0.93 TSHR (0.53)
SCHEMBL147796 0.92
Bromide SCHEMBL30994910 0.89 TSHR (0.47)
SCHEMBL28097444 0.89 TSHR (0.47)
SCHEMBL13538918 0.87 TSHR (0.47)
SCHEMBL788179 0.85 TSHR (0.44)
SCHEMBL5424151 0.81 ALDH1A1 (0.43)
SCHEMBL27856299 0.81 TSHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1993 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118787-A Process method for separating impurity-containing dichlorotoluene isomer 中盐常州化工股份有限公司 2024-12-13 CN claimed
CN-114988982-B Method for synthesizing 3, 5-dichlorotoluene through isomerization 江苏聚由新材料科技有限公司 2024-12-03 CN claimed
CN-118955242-A Method for preparing m-dichlorobenzene and 3, 5-dichlorotoluene by one-pot method 帕潘纳(北京)科技有限公司 2024-11-15 CN claimed
CN-118894759-A Preparation method of 3, 5-dichlorotoluene 帕潘纳(北京)科技有限公司 2024-11-05 CN claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
CN-114988982-A Method for isomerizing and synthesizing 3, 5-dichlorotoluene 江苏超跃化学有限公司 2022-09-02 CN claimed
CN-111548644-B Synthetic method of phthalocyanine blue dye 浙江瑞华化工有限公司 2022-08-26 CN claimed
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-03-15 US claimed
EP-3728235-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP claimed
US-6140342-A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR; USED TO ELEVATE CERTAIN PLASMA LIPID LEVELS, INCLUDING HIGH DENSITY LIPOPROTEIN-CHOLESTEROL AND TO LOWER CERTAIN OTHER PLASMA LIPID LEVELS, SUCH AS LDL-CHOLESTEROL AND TRIGLYCERIDES PFIZER INC. (US) 2000-10-31 US claimed
WO-2000017164-A1 4-CARBOXYAMINO-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS PFIZER PRODUCTS INC. (US) 2000-03-30 WO claimed
EP-0987251-A1 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as CETP inhibitors Pfizer Products Inc. (US) 2000-03-22 EP claimed
EP-0246673-B1 PROCESS FOR SEPARATING A CHLOROTOLUENE ISOMER TORAY INDUSTRIES, INC. (JP) 1991-09-11 EP claimed
EP-0125077-B1 ADSORPTIVE SEPARATION PROCESS TORAY INDUSTRIES, INC. (JP) 1989-06-28 EP claimed
US-4774371-A ISOMERIZATION OF DICHLOROTOLUENES TORAY INDUSTRIES, INC. (JP) 1988-09-27 US claimed
US-4748245-A Process for making phenylthiopyrimidines STAUFFER CHEMICAL COMPANY (US) 1988-05-31 US claimed
EP-0246673-A1 Process for separating a chlorotoluene isomer TORAY INDUSTRIES, INC. (JP) 1987-11-25 EP claimed
US-4537714-A Process for the preparation of lower alkyl esters of N-L-α-aspartyl-L-phenylalanine and of new intermediates for their preparation EPROVA AG FORSCHUNGSINSTITUT (CH) 1985-08-27 US claimed
EP-0125077-A1 Adsorptive separation process TORAY INDUSTRIES, INC. (JP) 1984-11-14 EP claimed