Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 3/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717415 | 0.83 | KDM1A (0.47) | ALDH1A1HTTSMN1; SMN2L3MBTL1ITK | |
| SCHEMBL16424284 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HTTSMN1; SMN2L3MBTL1ITK | |
| SCHEMBL22468588 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HTTSMN1; SMN2L3MBTL1ITK | |
| SCHEMBL15382055 | 0.74 | KIT (0.43) | MAP4K1KITKDM5B | |
| SCHEMBL16594168 | 0.73 | KIT (0.36) | KITKDRKDM5BEP300 | |
| SCHEMBL17480021 | 0.71 | KIT (0.42) | MAP4K1KITKDM5B | |
| SCHEMBL4730942 | 0.71 | ALDH1A1 (0.64) | ALDH1A1HTTSMN1; SMN2L3MBTL1KIT | |
| SCHEMBL21719735 | 0.70 | KDM1A (0.47) | ALDH1A1HTTSMN1; SMN2L3MBTL1KDM1A | |
| SCHEMBL1582031 | 0.69 | KIT (0.43) | ALDH1A1MAP4K1KITKDM5B | |
| SCHEMBL14149258 | 0.69 | KIT (0.43) | MAP4K1KITKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832734-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-04 | — | — | EP | disclosed |