Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16423792 | 0.85 | JAK2 (0.32) | JAK2KIT | |
| SCHEMBL16423952 | 0.77 | MAPT (0.41) | L3MBTL1 | |
| SCHEMBL16594188 | 0.76 | GRIA1 (0.30) | — | |
| SCHEMBL15652485 | 0.75 | KIT (0.49) | JAK2KITL3MBTL1MAP4K1 | |
| SCHEMBL15651314 | 0.74 | LRRK2 (0.38) | L3MBTL1ARMAP4K1 | |
| SCHEMBL15652469 | 0.74 | LRRK2 (0.42) | JAK2L3MBTL1AR | |
| SCHEMBL16594174 | 0.74 | KIT (0.31) | KITL3MBTL1 | |
| SCHEMBL22061397 | 0.72 | KIT (0.33) | KIT | |
| SCHEMBL15059198 | 0.72 | PDK2 (0.38) | KIT | |
| SCHEMBL16423182 | 0.71 | KIT (0.35) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832734-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-04 | — | — | EP | disclosed |