Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061450 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL15652485 | 0.78 | KIT (0.49) | KIT | |
| SCHEMBL16423182 | 0.77 | KIT (0.35) | KIT | |
| SCHEMBL15650977 | 0.75 | KDM5B (0.39) | KIT | |
| SCHEMBL573656 | 0.74 | MAPT (0.33) | — | |
| SCHEMBL16423791 | 0.71 | KIT (0.32) | KIT | |
| SCHEMBL23229773 | 0.70 | PDK2 (0.39) | KIT | |
| SCHEMBL15059198 | 0.70 | PDK2 (0.38) | KIT | |
| SCHEMBL23210319 | 0.70 | — | — | |
| SCHEMBL16423792 | 0.70 | JAK2 (0.32) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112700-A1 | 9-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2020-06-04 | — | — | WO | disclosed |