Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424232 | 0.85 | JAK2 (0.35) | JAK2KIT | |
| SCHEMBL16594188 | 0.74 | GRIA1 (0.30) | — | |
| SCHEMBL15652485 | 0.73 | KIT (0.49) | JAK2KIT | |
| SCHEMBL15651314 | 0.72 | LRRK2 (0.38) | — | |
| SCHEMBL16594174 | 0.71 | KIT (0.31) | KIT | |
| SCHEMBL12479083 | 0.71 | L3MBTL1 (0.42) | — | |
| SCHEMBL22061397 | 0.70 | KIT (0.33) | KIT | |
| SCHEMBL15650642 | 0.69 | MAP4K4 (0.41) | — | |
| SCHEMBL16423182 | 0.69 | KIT (0.35) | KIT | |
| SCHEMBL15651578 | 0.69 | HCRTR1 (0.37) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832734-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-04 | — | — | EP | disclosed |