Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.67 |
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12154226 | 0.91 | THRB (0.52) | THRBKMT2ALMNAHPGDL3MBTL1 | |
| SCHEMBL16425348 | 0.89 | THRB (0.52) | THRBKMT2AMEN1LMNAHPGD | |
| SCHEMBL15425180 | 0.88 | THRB (0.62) | THRBTHRAKMT2AMEN1LMNA | |
| SCHEMBL16425371 | 0.87 | THRB (0.50) | THRBKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL14010347 | 0.87 | THRB (0.67) | THRBTHRAKMT2AMEN1LMNA | |
| SCHEMBL15582417 | 0.87 | THRB (0.49) | THRBKMT2ALMNAHPGDL3MBTL1 | |
| SCHEMBL12404405 | 0.86 | THRB (0.67) | THRBTHRAKMT2AMEN1LMNA | |
| SCHEMBL14088484 | 0.86 | THRB (0.65) | THRBTHRAKMT2AMEN1LMNA | |
| SCHEMBL13614369 | 0.85 | THRB (0.86) | THRBTHRAKMT2AMEN1LMNA | |
| SCHEMBL16900323 | 0.85 | THRB (0.47) | THRBLMNAHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150029446-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICAL ANISOTROPIC FILM | JNC PETROCHEMICAL CORPORATION (JP) | 2015-01-29 | — | — | US | disclosed |