Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.65 |
| ▸ | THRA | P10827 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RARB | P10826 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010347 | 0.99 | THRB (0.67) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14010397 | 0.95 | THRB (0.60) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL12154170 | 0.90 | THRB (0.62) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14010389 | 0.90 | THRB (0.64) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL12154162 | 0.88 | RARB (0.58) | THRBRARB | |
| SCHEMBL16230828 | 0.88 | RARB (0.58) | THRBRARB | |
| SCHEMBL14010388 | 0.87 | RARB (0.56) | THRBRARBCYP3A4 | |
| SCHEMBL14010395 | 0.87 | TSHR (0.56) | THRBRARBCYP3A4 | |
| SCHEMBL19930191 | 0.86 | THRB (0.64) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL16425367 | 0.86 | THRB (0.67) | THRBTHRAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |