SCHEMBL16425620

SCHEMBL16425620

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2O[C@@H](N=O)[C@@H](O[C@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5N)[C@H](OCC5CCCCC5)C4O)[C@H](C)C3N)C(O)C2OS(=O)(=O)O)[C@H](O)C1N

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 6/20 0.47
▸ SERPINC1 P01008 2/20 0.42
▸ CXCL10 P02778 1/20 0.36
▸ CXCL8 P10145 1/20 0.36
▸ CCL2 P13500 1/20 0.36
▸ CCL5 P13501 1/20 0.36
▸ CXCL12 P48061 1/20 0.36
▸ FGF1 P05230 2/20 0.36
▸ BDNF P23560 3/20 0.35
▸ PTN P21246 2/20 0.35
▸ MDK P21741 2/20 0.35
▸ HPSE Q9Y251 4/20 0.31
▸ BLM P54132 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16425617 0.96 F10 (0.48) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425611 0.94 F10 (0.50) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425613 0.93 F10 (0.50) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425616 0.93 F10 (0.49) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16418343 0.90 F10 (0.58) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425621 0.89 F10 (0.47) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL17770817 0.84 F10 (0.53) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425608 0.84 F10 (0.58) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425607 0.84 F10 (0.58) F10SERPINC1CXCL10CXCL8CCL2
SCHEMBL16425606 0.80 F10 (0.52) F10SERPINC1CXCL10CXCL8CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150031866-A1 PROCESS FOR THE PRODUCTION OF FONDAPARINUX SODIUM SCINOPHARM TAIWAN, LTD. (TW) 2015-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031866-A1 PROCESS FOR THE PRODUCTION OF FONDAPARINUX SODIUM PF4, ABCC4, KCNH1 F10 119/4885SERPINC1 190/4885CXCL10 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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