Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643131 | 0.91 | PDE2A (0.45) | PDE2A | |
| SCHEMBL1642931 | 0.91 | PDE2A (0.40) | PDE2ASCN9A | |
| SCHEMBL1643215 | 0.87 | PDE2A (0.43) | PDE2ASCN9A | |
| SCHEMBL1643049 | 0.87 | PDE2A (0.38) | PDE2ASCN9A | |
| SCHEMBL1284979 | 0.86 | PDE2A (0.46) | PDE2ASCN9A | |
| SCHEMBL1644472 | 0.85 | PDE2A (0.37) | PDE2ASCN9A | |
| SCHEMBL1644195 | 0.85 | PDE2A (0.48) | PDE2ASCN9A | |
| SCHEMBL1644517 | 0.85 | PDE2A (0.37) | PDE2ASCN9A | |
| SCHEMBL1643884 | 0.84 | PDE2A (0.49) | PDE2ASCN9A | |
| SCHEMBL1645545 | 0.84 | PDE2A (0.42) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088746-A1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | PFIZER INC. (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088746-A1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | TRPV1, TRPA1, TRPV2 | PDE2A 1116/4885SCN9A 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.