Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 3/20 | 0.38 |
| ▸ | PRKACG | P22612 | 3/20 | 0.38 |
| ▸ | PRKACB | P22694 | 3/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14757656 | 1.00 | PRKACA (0.38) | PRKACAPRKACGPRKACBBAZ2ADHODH | |
| Hydrochloric Acid SCHEMBL17597383 | 0.99 | PRKACA (0.37) | PRKACAPRKACGPRKACBBAZ2ADHODH | |
| SCHEMBL16428839 | 0.95 | DDR1 (0.34) | PRKACAPRKACGPRKACBMCHR1 | |
| SCHEMBL16428731 | 0.95 | DDR1 (0.34) | PRKACAPRKACGPRKACBMCHR1 | |
| SCHEMBL14744982 | 0.95 | BAZ2A (0.37) | PRKACAPRKACGPRKACBBAZ2AMCHR1 | |
| Hydrochloric Acid SCHEMBL17597199 | 0.94 | DPP4 (0.34) | PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL17597198 | 0.94 | BAZ2A (0.36) | PRKACAPRKACGPRKACBBAZ2AMCHR1 | |
| SCHEMBL14740825 | 0.93 | FAAH (0.33) | FAAH | |
| SCHEMBL14745342 | 0.93 | DHODH (0.38) | DHODHMCHR1FAAHMAOA | |
| SCHEMBL14745341 | 0.93 | DHODH (0.38) | DHODHMCHR1FAAHMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409905-B2 | Antibacterial compounds and methods for use | PTC THERAPEUTICS, INC. (US) | 2016-08-09 | — | — | US | claimed |
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2015-02-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | MRPL21, SLC11A2, CLPP | PRKACA 1844/4885PRKACG 1705/4885PRKACB 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.