Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 5/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428953 | 0.84 | PIK3C3 (0.41) | BRD4PIK3C3ALOX5APFEN1KDM5A | |
| SCHEMBL14745332 | 0.77 | PIK3C3 (0.42) | BRD4PIK3C3ALOX5APFEN1SYK | |
| SCHEMBL14745155 | 0.68 | PIK3C3 (0.40) | BRD4PIK3C3ALOX5APFEN1KDM5A | |
| SCHEMBL30052190 | 0.67 | BRD4 (0.45) | BRD4PIK3C3ALOX5APFEN1SYK | |
| SCHEMBL15730145 | 0.66 | BRD4 (0.53) | BRD4PIK3C3ALOX5APFEN1SYK | |
| SCHEMBL16428706 | 0.66 | BRD4 (0.40) | BRD4ALDH1A1 | |
| SCHEMBL1269027 | 0.65 | TYR (0.45) | BRD4PIK3C3APPQPCTQPCTL | |
| SCHEMBL586478 | 0.65 | BRD4 (0.51) | BRD4PIK3C3SYKAPPQPCT | |
| SCHEMBL23600955 | 0.65 | BRD4 (0.52) | BRD4PIK3C3SYKQPCTQPCTL | |
| SCHEMBL16568205 | 0.65 | PGR (0.43) | APPQPCTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409905-B2 | Antibacterial compounds and methods for use | PTC THERAPEUTICS, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | MRPL21, SLC11A2, CLPP | BRD4 2439/4885PIK3C3 1025/4885ALOX5AP 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.