Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 12/20 | 0.94 |
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21332117 | 1.00 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| SCHEMBL69729 | 0.97 | SRD5A2 (1.00) | SRD5A2TSHRTP53CA1CA2 | |
| SCHEMBL2407327 | 0.97 | SRD5A2 (1.00) | SRD5A2TSHRTP53CA1CA2 | |
| SCHEMBL11598432 | 0.94 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| SCHEMBL29013646 | 0.94 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| Hydrochloric Acid SCHEMBL9236217 | 0.94 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| Potassium SCHEMBL30444322 | 0.94 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| Hydrochloric Acid SCHEMBL894685 | 0.94 | SRD5A2 (0.94) | SRD5A2TSHRTP53CA1CA2 | |
| Terephthalic Acid SCHEMBL688187 | 0.90 | TSHR (0.92) | SRD5A2TSHRTP53CA1CA2 | |
| Terephthalic Acid SCHEMBL4607897 | 0.90 | TSHR (0.92) | SRD5A2TSHRTP53CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321017-B2 | Gas-separation membrane | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150033945-A1 | GAS-SEPARATION MEMBRANE | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-02-05 | — | — | US | disclosed |