Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL688187 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL3045636 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL108476 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL996091 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553993-A | A kind of soundproof fiberboard | 南京明轮有色金属有限公司 | 2019-04-02 | — | — | CN | claimed |
| WO-2022181558-A1 | HEAT-RESISTANT HIGH-TOUGHNESS FIBER, PRODUCTION METHOD THEREFOR, AND HEAT-RESISTANT HIGH-TOUGHNESS FILM | 帝人株式会社 | 2022-09-01 | — | — | WO | disclosed |
| EP-3006610-B1 | ORGANIC RESIN NON-CRIMPED STAPLE FIBER | TEIJIN LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-20160177476-A1 | ORGANIC RESIN NON-CRIMPED STAPLE FIBER | TEIJIN LIMITED (JP) | 2016-06-23 | — | — | US | disclosed |
| EP-3006610-A1 | ORGANIC RESIN NON-CRIMPED STAPLE FIBER | Teijin Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-1945693-B1 | POLYARYLATE-SILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-08-13 | — | — | EP | disclosed |
| CN-101683005-B | Circuit materials, multilayer circuits, and methods of manufacture thereof | WORLD PROPERTIES INC | 2012-12-05 | — | — | CN | disclosed |
| CN-101683005-A | Circuit materials, multilayer circuits, and methods of manufacture thereof | WORLD PROPERTIES INC | 2010-03-24 | — | — | CN | disclosed |
| CN-101331172-A | Polyarylate-siloxane copolymers | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-12-24 | — | — | CN | disclosed |
| EP-1945693-A1 | POLYARYLATE-SILOXANE COPOLYMERS | Momentive Performance Materials Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| CN-100339153-C | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS INC (US) | 2007-09-26 | — | — | CN | disclosed |
| WO-2007047083-A1 | POLYARYLATE-SILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070083026-A1 | Polyarylate-siloxane copolymers | GENERAL ELECTRIC COMPANY (US) | 2007-04-12 | — | — | US | disclosed |
| CN-1646203-A | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS INC (US) | 2005-07-27 | — | — | CN | disclosed |
| US-4705833-A | POLYIMIDES, EPOXY RESINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0188337-A2 | Thermosettable heat-resistant epoxy resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-23 | — | — | EP | disclosed |