Terephthalic Acid

Terephthalic Acid

SCHEMBL688187

Br.Br.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.92
TP53 P04637 1/20 0.92
SRD5A2 P31213 4/20 0.75
CA1 P00915 3/20 0.71
CA2 P00918 3/20 0.71
CA12 O43570 1/20 0.71
CA3 P07451 1/20 0.71
TYR P14679 1/20 0.71
DRD1 P21728 1/20 0.71
CA4 P22748 1/20 0.71
CA6 P23280 1/20 0.71
CA5A P35218 1/20 0.71
CA7 P43166 1/20 0.71
CA9 Q16790 1/20 0.71
CA14 Q9ULX7 1/20 0.71
CA5B Q9Y2D0 1/20 0.71
NAPRT Q6XQN6 2/20 0.69
DAO P14920 1/20 0.69
ALDH1A1 P00352 2/20 0.67
ALOX15 P16050 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4607897 1.00 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL3045636 0.96 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL175823 0.96 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL1655 0.96 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL2511919 0.96 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL5053781 0.96 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL25381766 0.92 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL108476 0.92 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL996091 0.92 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL20704876 0.92 TSHR (0.92) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229586-A1 POLYAMIDE GREASE THICKENING AGENT INV NYLON CHEMICALS AMERICAS, LLC (US) 2025-11-06 WO claimed
WO-2025229586-A1 POLYAMIDE GREASE THICKENING AGENT INV NYLON CHEMICALS AMERICAS, LLC (US) 2025-11-06 WO disclosed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-20230390890-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON TOKUYAMA CORPORATION (JP) 2023-12-07 US disclosed
EP-4286439-A1 HOLLOW MICROBALLOON Tokuyama Corporation (JP) 2023-12-06 EP disclosed
EP-4205904-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON Tokuyama Corporation (JP) 2023-07-05 EP disclosed
US-20230203234-A1 HOLLOW MICROBALLOONS TOKUYAMA CORPORATION (JP) 2023-06-29 US disclosed
US-20230151179-A1 HOLLOW MICROBALLOONS FOR CMP POLISHING PAD TOKUYAMA CORPORATION (JP) 2023-05-18 US disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
WO-2022045018-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON 株式会社トクヤマ 2022-03-03 WO disclosed
EP-1820667-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-22 EP disclosed
EP-0659796-B1 Liquid crystalline polyesters NIPPON OIL CO LTD (JP) 1999-03-17 EP disclosed
EP-0608991-B1 Liquid crystalline polyesters NIPPON OIL CO LTD (JP) 1997-05-21 EP disclosed
US-5432249-A Liquid crystalline polyesters NIPPON OIL COMPANY, LIMITED (JP) 1995-07-11 US disclosed
EP-0659796-A2 Liquid crystalline polyesters NIPPON OIL COMPANY, LIMITED (JP) 1995-06-28 EP disclosed
US-5391688-A Aromatic co-polyesters having glass transition temperatures lower than the liquid crystal transition point NIPPON OIL COMPANY, LIMITED (JP) 1995-02-21 US disclosed
US-5358661-A Stable, soluble polymers from 4,4*-biphenyldicarboxylic acid, 2,6-naphthalenedicarboxylic acid and/or terephthalic acid, and substituted 1,4-butanediols NIPPON OIL COMPANY, LIMITED (JP) 1994-10-25 US disclosed
EP-0608991-A1 Liquid crystalline polyesters NIPPON OIL CO. LTD. (JP) 1994-08-03 EP disclosed
US-4278786-A BIS/P-AMINOPHENOL ETHER OF A BISPHENOL HITACHI, LTD. (JP) 1981-07-14 US disclosed
US-4172938-A Process for producing polyamides with lactam or urea solvent and CaCl2 TEIJIN LIMITED (JP) 1979-10-30 US disclosed