Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430635 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL1360526 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL13875637 | 0.78 | PTGS1 (0.50) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL699014 | 0.78 | PTGS1 (0.47) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL1352493 | 0.77 | MEN1 (0.78) | NPSR1SMN1; SMN2HSD17B10PTGS1MEN1 | |
| SCHEMBL1362336 | 0.76 | PTGS1 (0.48) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL3135074 | 0.76 | PTGS1 (0.48) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL2103789 | 0.76 | PTGS1 (0.46) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL404470 | 0.76 | PTGS1 (0.51) | ALDH1A1KDM4ENPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL1353546 | 0.76 | NPC1 (0.71) | KDM4ESMN1; SMN2PTGS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016293-A1 | (BENZENESULFONYLAMINO)BENZAMIDE DERIVATIVE, AND SHIP2 INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人 富山大学 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015016293-A1 | (BENZENESULFONYLAMINO)BENZAMIDE DERIVATIVE, AND SHIP2 INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人 富山大学 (JP) | 2015-02-05 | — | — | WO | disclosed |