Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133568 | 0.83 | ABCC9 (0.52) | SMN1; SMN2NPSR1ALDH1A1KCNJ11ABCC9 | |
| SCHEMBL3466694 | 0.80 | RXFP1 (0.46) | KCNJ11ABCC9ABCC8KCNJ8MEN1 | |
| SCHEMBL13875637 | 0.78 | PTGS1 (0.50) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL404470 | 0.76 | PTGS1 (0.51) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL1813928 | 0.76 | PTGS1 (0.51) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL1815240 | 0.76 | PTGS1 (0.42) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL16430397 | 0.76 | ALDH1A1 (0.57) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL28496399 | 0.76 | PTGS1 (0.53) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL1767262 | 0.76 | PTGS1 (0.53) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E | |
| SCHEMBL3137498 | 0.75 | PTGS1 (0.52) | PTGS1SMN1; SMN2NPSR1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618173-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2013-12-31 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| EP-2203052-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049845-A2 | BISAMIDE DERIVATIVES AND THEIR USE AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240712-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, ACHE | PTGS1 1061/4885SMN1; SMN2 611/4885NPSR1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.