Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | TCF4 | P15884 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430718 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430504 | 0.86 | TCF4 (0.69) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16431446 | 0.85 | TCF4 (0.65) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430653 | 0.85 | TCF4 (0.54) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430707 | 0.85 | TCF4 (0.54) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430148 | 0.84 | TCF4 (0.66) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430799 | 0.84 | TCF4 (0.52) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL16430813 | 0.82 | TCF4 (0.66) | MEN1KMT2ATCF4CTNNB1EGFR | |
| SCHEMBL29978644 | 0.82 | MEN1 (0.71) | MEN1KMT2AMAPTPKMSIRT2 | |
| SCHEMBL665214 | 0.82 | MEN1 (0.71) | MEN1KMT2AMAPTPKMSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016293-A1 | (BENZENESULFONYLAMINO)BENZAMIDE DERIVATIVE, AND SHIP2 INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人 富山大学 (JP) | 2015-02-05 | — | — | WO | disclosed |