SCHEMBL16433752

SCHEMBL16433752

c1ccc(-c2c3ccccc3c(-c3ccc4ccc5cccnc5c4n3)c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.50
CCR8 P51685 5/20 0.50
LMNA P02545 4/20 0.50
CCR5 P51681 3/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
CYP3A4 P08684 2/20 0.50
HTT P42858 2/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
MMP2 P08253 1/20 0.50
CYP2D6 P10635 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
MMP8 P22894 1/20 0.50
THPO P40225 1/20 0.50
MTOR P42345 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20456936 0.97 CCR1 (0.47) CCR1CCR8LMNACCR5KDM4E
SCHEMBL1103060 0.94 CCR1 (0.47) CCR1CCR8LMNACCR5KDM4E
SCHEMBL17522017 0.92 CCR1 (0.48) CCR1CCR8LMNACCR5KDM4E
SCHEMBL29444813 0.92 CCR1 (0.59) CCR1CCR8LMNACCR5KDM4E
SCHEMBL2448839 0.92 CCR1 (0.59) CCR1CCR8LMNACCR5KDM4E
SCHEMBL17899274 0.91 CCR1 (0.47) CCR1CCR8LMNACCR5KDM4E
SCHEMBL1102749 0.91 TNF (0.41) CCR1CCR8LMNACCR5KDM4E
SCHEMBL21308886 0.91 TOP1 (0.43) CCR1CCR8LMNACCR5KDM4E
SCHEMBL13158747 0.91 CCR1 (0.41) CCR1CCR8LMNACCR5KDM4E
SCHEMBL17491077 0.90 CCR1 (0.46) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210202845-A1 ORGANIC ELECTRIC ELEMENT, DISPLAY PANEL COMPRISING THE SAME AND DISPLAY DEVICE COMPRISING THE SAME LG DISPLAY CO., LTD. (KR) 2021-07-01 US disclosed
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150069351-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-03-12 US disclosed
EP-2833429-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
EP-2833700-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 CCR1 2156/4885CCR8 2584/4885LMNA 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.