SCHEMBL2448839

SCHEMBL2448839

c1cnc2c(c1)ccc1ccc(-c3c4ccccc4c(-c4ccc5ccc6cccnc6c5n4)c4ccccc34)nc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.59
CCR8 P51685 5/20 0.59
MAPT P10636 5/20 0.59
LMNA P02545 4/20 0.59
KDM4E B2RXH2 4/20 0.59
CCR5 P51681 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CYP3A4 P08684 2/20 0.59
MMP2 P08253 2/20 0.59
TSHR P16473 2/20 0.59
TP53 P04637 2/20 0.59
HSP90AA1 P07900 2/20 0.59
HTT P42858 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
GMNN O75496 1/20 0.59
CYP2D6 P10635 1/20 0.59
MMP9 P14780 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59
MMP8 P22894 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444813 1.00 CCR1 (0.59) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL13015742 0.95 MAPT (0.53) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL1102872 0.95 CCR1 (0.53) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL16433752 0.92 CCR1 (0.50) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL23502264 0.92 CCR1 (0.50) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL17756850 0.91 CCR1 (0.53) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL13145321 0.91 MAPT (0.48) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL12955082 0.91 CCR1 (0.48) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL1102526 0.89 CCR1 (0.47) CCR1CCR8MAPTLMNAKDM4E
SCHEMBL20456936 0.89 CCR1 (0.47) CCR1CCR8MAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
EP-3960744-B1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2024-08-21 EP disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-11800785-B2 Material for organic device and organic electroluminescent device using the same KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-10-24 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11723263-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-08 US disclosed
US-20130105787-A1 LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2013-05-02 US disclosed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20070212568-A1 Organic Electroluminescent Device CHISSO CORPORATION (JP) 2007-09-13 US disclosed
US-20060110622-A1 Organic electroluminescent device LG ELECTRONICS, INC. (KR) 2006-05-25 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
EP-1624501-A2 Organic electroluminescent device LG Electronics, Inc. (KR) 2006-02-08 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC CCR1 992/4885CCR8 773/4885MAPT 1196/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 CCR1 59/4885CCR8 689/4885MAPT 4416/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR CCR1 300/4885CCR8 943/4885MAPT 4577/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 CCR1 1160/4885CCR8 2160/4885MAPT 25/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 CCR1 4677/4885CCR8 2085/4885MAPT 3249/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 CCR1 3574/4885CCR8 2326/4885MAPT 949/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 CCR1 3574/4885CCR8 2326/4885MAPT 949/4885
US-11723263-B2 Organic electroluminescent element NR4A3, AFF4, NR4A1 CCR1 1726/4885CCR8 1873/4885MAPT 3561/4885
US-11800785-B2 Material for organic device and organic electroluminescent device using the same RER1, LEF1, CHRM1 CCR1 255/4885CCR8 1880/4885MAPT 4476/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 CCR1 1179/4885CCR8 2416/4885MAPT 3264/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 CCR1 1580/4885CCR8 3021/4885MAPT 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.