Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | YAP1 | P46937 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687855 | 0.92 | MEN1 (0.40) | CHRM3MEN1KMT2AYAP1SMN1; SMN2 | |
| SCHEMBL12505895 | 0.91 | MEN1 (0.38) | CHRM3MEN1KMT2AYAP1SMN1; SMN2 | |
| SCHEMBL16434615 | 0.86 | ADAMTS4 (0.39) | KMT2A | |
| SCHEMBL16434636 | 0.86 | USP2 (0.38) | MEN1KMT2A | |
| SCHEMBL12688030 | 0.85 | KMT2A (0.40) | CHRM3MEN1KMT2ASMN1; SMN2CCR3 | |
| SCHEMBL16434635 | 0.84 | YAP1 (0.39) | CHRM3YAP1 | |
| SCHEMBL16434637 | 0.82 | MEN1 (0.38) | CHRM3MEN1KMT2ACCR3 | |
| SCHEMBL16434640 | 0.74 | TP53 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12505886 | 0.74 | YAP1 (0.38) | YAP1 | |
| SCHEMBL12687639 | 0.71 | MAPK8 (0.39) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661424-B1 | 4-(ORTHO-SUBSTITUTED-PHENYL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE COMPOUNDS AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-12 | — | — | EP | disclosed |
| US-8946453-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-20140011845-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011845-A1 | CHEMICAL COMPOUNDS | CYP1B1, CYP1A1, NQO1 | CHRM3 2072/4885MEN1 409/4885KMT2A 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.