Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106913 | 0.65 | ALDH1A1 (0.42) | GSK3AGSK3BALDH1A1USP2ALOX15 | |
| SCHEMBL10614240 | 0.65 | ALDH1A1 (0.42) | GSK3AGSK3BALDH1A1USP2ALOX15 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.64 | GAA (0.67) | ALDH1A1ALOX15CYP4F2CYP4A11CYP1A2 | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.64 | GAA (0.67) | ALDH1A1ALOX15CYP4F2CYP4A11CYP1A2 | |
| SCHEMBL15391156 | 0.64 | GSK3A (0.41) | GSK3AGSK3BALDH1A1KAT2BUSP2 | |
| SCHEMBL26970249 | 0.64 | ALDH1A1 (0.47) | ALDH1A1USP2ALOX15TDP1CYP4F2 | |
| SCHEMBL20569201 | 0.64 | ALDH1A1 (0.47) | GSK3AGSK3BALDH1A1USP2ALOX15 | |
| SCHEMBL27740322 | 0.64 | ALDH1A1 (0.51) | ALDH1A1USP2ALOX15TDP1CYP4F2 | |
| SCHEMBL18623243 | 0.63 | ALDH1A1 (0.50) | ALDH1A1USP2ALOX15TDP1CYP4F2 | |
| Succinic Acid Diethyl Ester SCHEMBL21815758 | 0.62 | GAA (0.63) | ALDH1A1ALOX15CYP4F2CYP4A11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024540-B | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2022-03-04 | — | — | CN | claimed |
| CN-113024540-A | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2021-06-25 | — | — | CN | claimed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | claimed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | claimed |
| CN-113980001-B | Pyrazolol-pyridazinone coupling compound, pharmaceutical composition thereof and application of pyrazolol-pyridazinone coupling compound in medicines | 贵州医科大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-113024540-B | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2022-03-04 | — | — | CN | disclosed |
| CN-108137513-B | Pyrimidine derivatives | ASKA 制药株式会社 | 2022-03-01 | — | — | CN | disclosed |
| CN-113980001-A | Pyrazole alcohol-pyridazinone coupling compound, pharmaceutical composition thereof and application thereof in medicines | 贵州医科大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113200850-A | Preparation method of alpha-acyloxyketone compound | 渭南师范学院 | 2021-08-03 | — | — | CN | disclosed |
| CN-113024540-A | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2021-06-25 | — | — | CN | disclosed |
| CN-105566110-B | A kind of synthetic method of polysubstituted 1 naphthols and its derivative | 南开大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-1694878-A | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | AVECIA LTD (GB) | 2005-11-09 | — | — | CN | disclosed |
| CN-1688582-A | Fused azole-pyrimidine derivatives | BAYER PHARMACEUTICALS CORP (US) | 2005-10-26 | — | — | CN | disclosed |
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005035507-A2 | 4-AMINOPYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-04-21 | — | — | WO | disclosed |
| EP-1486493-A1 | 3-HYDROXY-3-(2-THIENYL)PROPIONAMIDE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING 3-AMINO-1-(2-THIENYL)-1-PROPANOL COMPOUND THEREFROM | Mitsubishi Chemical Corporation (JP) | 2004-12-15 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | GSK3A 2729/4885GSK3B 3103/4885ALDH1A1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.