Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848810 | 0.74 | ALDH1A1 (0.61) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.72 | GAA (0.67) | ALDH1A1ALOX15CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.72 | GAA (0.67) | ALDH1A1ALOX15CYP1A2GAAMGAM | |
| SCHEMBL26970249 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL27740322 | 0.72 | ALDH1A1 (0.51) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| SCHEMBL18623243 | 0.71 | ALDH1A1 (0.50) | ALDH1A1ALOX15TDP1USP2CYP1A2 | |
| Succinic Acid Diethyl Ester SCHEMBL4324913 | 0.70 | GAA (0.63) | ALDH1A1ALOX15CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL29494609 | 0.70 | GAA (0.63) | ALDH1A1ALOX15CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL21815758 | 0.70 | GAA (0.63) | ALDH1A1ALOX15CYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL28853161 | 0.70 | GAA (0.63) | ALDH1A1ALOX15CYP1A2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-05-15 | — | — | US | disclosed |
| US-20230321267-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-11759526-B2 | Method and molecules | MEDIMMUNE, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| EP-4223319-A2 | METHOD AND MOLECULES | MedImmune, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3630732-B1 | METHOD AND MOLECULES | MEDIMMUNE LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20200206359-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-02 | — | — | US | disclosed |
| EP-3630732-A1 | METHOD AND MOLECULES | Medimmune, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018218093-A1 | METHOD AND MOLECULES | MEDIMMUNE, LLC (US) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | PAICS, EPCAM, SQLE | ALDH1A1 27/4885ALOX15 38/4885TDP1 4790/4885 |
| US-20200206359-A1 | Method And Molecules | PAICS, EPCAM, SQLE | ALDH1A1 27/4885ALOX15 38/4885TDP1 4790/4885 |
| US-20230321267-A1 | Method And Molecules | PAICS, EPCAM, SQLE | ALDH1A1 27/4885ALOX15 38/4885TDP1 4790/4885 |
| US-11759526-B2 | Method and molecules | PAICS, EPCAM, SQLE | ALDH1A1 27/4885ALOX15 38/4885TDP1 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.