SCHEMBL16436244

SCHEMBL16436244

C=CC(=O)Oc1ccc(-c2ccc(-c3ccc(OC(=O)C(=C)C)cc3F)o2)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.36
KMT2A Q03164 3/20 0.34
THRB P10828 2/20 0.34
ATM Q13315 2/20 0.34
NQO2 P16083 3/20 0.33
STS P08842 1/20 0.32
GAPDH P04406 1/20 0.32
MAOB P27338 1/20 0.32
MEN1 O00255 1/20 0.31
ADORA3 P0DMS8 1/20 0.30
SLC9A1 P19634 1/20 0.30
APP P05067 1/20 0.30
CYP2C19 P33261 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16436206 1.00 ELANE (0.36) ELANEKMT2ATHRBATMNQO2
SCHEMBL16436233 0.93 ELANE (0.41) ELANEKMT2AATMNQO2STS
SCHEMBL16436198 0.91 THRB (0.38) THRBNQO2STSGAPDHMAOB
SCHEMBL16436316 0.90 THRB (0.37) THRBNQO2STSGAPDHMAOB
SCHEMBL16436356 0.88 PTGS2 (0.31) STSMAOBPTGS2
SCHEMBL16436243 0.88 ELANE (0.37) ELANEKMT2ATHRBATMNQO2
SCHEMBL16436241 0.88 ELANE (0.37) ELANEKMT2ATHRBATMNQO2
SCHEMBL16436272 0.88 ELANE (0.40) ELANEKMT2AATMNQO2STS
SCHEMBL18194819 0.87 ELANE (0.42) ELANEKMT2ATHRBATMGAPDH
SCHEMBL18194796 0.87 ELANE (0.42) ELANEKMT2ATHRBATMGAPDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315603-B2 Polymerizable compound having oxygen-containing five-membered ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-04-19 US disclosed
US-9315603-B2 Polymerizable compound having oxygen-containing five-membered ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-02-05 US disclosed
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE OCIAD1, OCIAD2, SCO2 ELANE 2946/4885KMT2A 3863/4885THRB 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.