Sugi Predict

Sugi Predict / Compounds / SCHEMBL16436320

SCHEMBL16436320

SCHEMBL16436320

C=C(C)C(=O)Oc1ccc2cc(-c3ccc(-c4ccc(OC(=O)C(=C)C)c(F)c4)o3)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.36
▸ PDE4A P27815 1/20 0.35
▸ CA12 O43570 2/20 0.35
▸ CA9 Q16790 2/20 0.35
▸ KMT2A Q03164 2/20 0.34
▸ ATM Q13315 1/20 0.34
▸ GAPDH P04406 1/20 0.34
▸ ADORA3 P0DMS8 1/20 0.34
▸ STS P08842 1/20 0.34
▸ PPARD Q03181 4/20 0.34
▸ FFAR1 O14842 2/20 0.34
▸ PPARA Q07869 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ GLA P06280 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ SCD O00767 1/20 0.33
▸ NQO2 P16083 2/20 0.33
▸ HSD17B1 P14061 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16436315 0.91 ELANE (0.42) ELANEPDE4AKMT2AATMADORA3
SCHEMBL16436317 0.87 ELANE (0.44) ELANECA12CA9KMT2AATM
SCHEMBL16436228 0.86 ELANE (0.36) ELANEPDE4AKMT2AATMADORA3
SCHEMBL16436323 0.86 RARA (0.34) ELANECA12CA9KMT2AADORA3
SCHEMBL16436246 0.86 THRB (0.36) ELANEPDE4AKMT2AATMADORA3
SCHEMBL16436342 0.84 KMT2A (0.38) ELANECA12CA9KMT2AATM
SCHEMBL16436225 0.82 MAPT (0.36) ELANEKMT2AATMSTSPPARD
SCHEMBL16436385 0.82 ELANE (0.44) ELANECA12CA9KMT2AATM
SCHEMBL16436380 0.81 KMT2A (0.38) ELANEPDE4AKMT2AATMGAPDH
SCHEMBL16436381 0.81 NQO2 (0.32) ELANEPDE4AKMT2ASTSKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315603-B2 Polymerizable compound having oxygen-containing five-membered ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-04-19 — — US disclosed
US-9315603-B2 Polymerizable compound having oxygen-containing five-membered ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-04-19 — — US disclosed
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-02-05 — — US disclosed
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150034871-A1 POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE OCIAD1, OCIAD2, SCO2 ELANE 2946/4885PDE4A 3691/4885CA12 822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.