SCHEMBL1643719

SCHEMBL1643719

CC(C)(C)c1ccc(C(C)(C)C)c(NC(=O)c2ccc3c4cccc5cccc(c6ccc(C(=O)Nc7cc(C(C)(C)C)ccc7C(C)(C)C)c2c36)c54)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 1/20 0.45
▸ KDM4E B2RXH2 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NR1H4 Q96RI1 6/20 0.40
▸ PPARD Q03181 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ TRPV1 Q8NER1 1/20 0.39
▸ DHPS P49366 1/20 0.39
▸ NLRP3 Q96P20 1/20 0.38
▸ CFTR P13569 3/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38
▸ ADRB3 P13945 1/20 0.38
▸ TBXA2R P21731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513078 0.96 MAPK14 (0.42) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL8878909 0.96 MAPK14 (0.42) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL8892902 0.86 BTK (0.38) KDM4EMEN1KMT2APOLBRAB9A
SCHEMBL1628380 0.82 MAPK14 (0.38) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL6756950 0.80 MAPK14 (0.48) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL5013031 0.79 MAPK14 (0.47) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL8885239 0.77 DHPS (0.47) MEN1KMT2ARAB9ASMN1; SMN2MAPT
SCHEMBL8885243 0.74 DHPS (0.55) MEN1KMT2ARAB9ASMN1; SMN2MAPT
SCHEMBL6521563 0.74 NR1H4 (0.43) MAPK14KDM4EMEN1KMT2APOLB
SCHEMBL8878972 0.73 MAPK14 (0.35) MAPK14KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716718-B1 OPTICALLY CONTROLLED OPTICAL-PATH-SWITCHING-TYPE OPTICAL SIGNAL TRANSMISSION APPARATUS, AND METHOD OF SWITCHING OPTICAL PATHS FOR OPTICAL SIGNALS DAINICHISEIKA COLOR CHEM (JP) 2012-10-31 — — EP claimed
EP-0227086-B1 CHEMILUMINESCENT COMPOSITION AMERICAN CYANAMID COMPANY (US) 1990-11-07 — — EP claimed
US-10903439-B2 Solid-state organic intermediate-band photovoltaic devices THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2021-01-26 — — US disclosed
US-20200280008-A1 SOLID-STATE ORGANIC INTERMEDIATE-BAND PHOTOVOLTAIC DEVICES UNITED STATES DEPARTMENT OF ENERGY 2020-09-03 — — US disclosed
US-10665803-B2 Solid-state organic intermediate-band photovoltaic devices THE TRUSTEEES OF PRINCETON UNIVERSITY (US) 2020-05-26 — — US disclosed
US-10256407-B2 Organic thin film transistors WAKE FOREST UNIVERSITY (US) 2019-04-09 — — US disclosed
US-20190097148-A1 SOLID-STATE ORGANIC INTERMEDIATE-BAND PHOTOVOLTAIC DEVICES UNITED STATES DEPARTMENT OF ENERGY 2019-03-28 — — US disclosed
US-20180159036-A1 METHOD OF MAKING AN ORGANIC THIN FILM TRANSISTOR UNIV WAKE FOREST (US) 2018-06-07 — — US disclosed
US-9882128-B2 Method of making an organic thin film transistor WAKE FOREST UNIVERSITY (US) 2018-01-30 — — US disclosed
US-20170092859-A1 METHOD OF MAKING AN ORGANIC THIN FILM TRANSISTOR UNIV WAKE FOREST (US) 2017-03-30 — — US disclosed
US-9530975-B2 Method of making an organic thin film transistor WAKE FOREST UNIVERSITY (US) 2016-12-27 — — US disclosed
EP-2898552-B1 ORGANIC THIN FILM TRANSISTORS AND METHODS OF MAKING THE SAME UNIV WAKE FOREST (US) 2016-03-23 — — EP disclosed
US-20150243916-A1 ORGANIC THIN FILM TRANSISTORS AND METHODS OF MAKING THE SAME WAKE FOREST UNIVERSITY (US) 2015-08-27 — — US disclosed
US-8366630-B2 Carbon nanotube structures in sensor apparatuses for analyzing biomarkers in breath samples TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2013-02-05 — — US disclosed
EP-2281193-B1 CARBON NANOTUBE STRUCTURES IN SENSOR APPARATUSES FOR ANALYZING BIOMARKERS IN BREATH SAMPLES TECHNION RES & DEV FOUNDATION (IL) 2012-08-15 — — EP disclosed
US-20110098591-A1 CARBON NANOTUBE STRUCTURES IN SENSOR APPARATUSES FOR ANALYZING BIOMARKERS IN BREATH SAMPLES TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2011-04-28 — — US disclosed
US-5326661-A Photorefractive polymers containing discrete photoconductive and electrooptical units HOECHST CELANESE CORP. (US) 1994-07-05 — — US disclosed
US-5184323-A Optical coupling of intersecting beams of electromagnetic radiation; potential gradients; molecular dipoles containing electron donor linked to electron acceptor through pi bonding system EASTMAN KODAK COMPANY (US) 1993-02-02 — — US disclosed
EP-0446154-A2 Photorefractive device EASTMAN KODAK COMPANY (US) 1991-09-11 — — EP disclosed
US-4999809-A Electrical biasing means for potential gradients, electromagnetic beams for images, multilayer elements EASTMAN KODAK COMPANY (US) 1991-03-12 — — US disclosed
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