Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643719 | 0.86 | MAPK14 (0.45) | CASP3CASP6CASP8NR1H4RAB9A | |
| SCHEMBL8878909 | 0.82 | MAPK14 (0.42) | CASP3CASP6CASP8NR1H4SERPINE1 | |
| SCHEMBL6513078 | 0.82 | MAPK14 (0.42) | CASP3CASP6CASP8NR1H4SERPINE1 | |
| SCHEMBL32667990 | 0.75 | KIF11 (0.51) | ACLYCASP3CASP6CASP8TNIK | |
| SCHEMBL8885239 | 0.74 | DHPS (0.47) | PLGKLK1KLK6KLKB1RAB9A | |
| SCHEMBL3261199 | 0.72 | HDAC8 (0.47) | NR1H4HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL330628 | 0.71 | TMPRSS4 (0.52) | PLGKLK1KLK6KLKB1NR1H4 | |
| SCHEMBL7217379 | 0.71 | ALDH1A1 (0.47) | ACLYNR1H4CYP2C9RAB9ANPC1 | |
| SCHEMBL2856806 | 0.70 | TDP1 (0.44) | PLGKLK1KLK6KLKB1NR1H4 | |
| SCHEMBL330902 | 0.70 | TMPRSS4 (0.70) | NR1H4TMPRSS4SERPINE1FLT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650513-A | Process for preparing perylene-3,4-dicarboxylic acid derivatives, the derivatives thus prepared and their use | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |