Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353741 | 0.95 | MEN1 (0.54) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL16353954 | 0.95 | MEN1 (0.54) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL5596775 | 0.85 | MEN1 (0.43) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL135077 | 0.83 | MEN1 (0.61) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL3248721 | 0.82 | MEN1 (0.56) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL27991187 | 0.82 | MEN1 (0.40) | MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL11278283 | 0.80 | MEN1 (0.58) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL12918863 | 0.80 | MEN1 (0.58) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL9705183 | 0.80 | MEN1 (0.58) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL16353752 | 0.78 | MEN1 (0.38) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420630-B2 | Pyrimidine derivatives | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2013-04-16 | — | — | US | claimed |
| EP-2090571-B1 | Pyrimidine derivates, medicaments comprising them, their use and process of their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-16 | — | — | EP | claimed |
| US-20100152167-A1 | PYRIMIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2010-06-17 | — | — | US | claimed |
| US-7550020-B2 | Chemical mechanical polishing aqueous dispersion and chemical mechanical polishing method | JSR CORPORATION (JP) | 2009-06-23 | — | — | US | claimed |
| EP-1438053-B1 | PYRIMIDINE DERIVATIVES, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS, USE AND METHOD FOR MAKING SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-09-10 | — | — | EP | claimed |
| EP-1077240-B1 | Aqueous dispersion for chemical mechanical polishing | JSR CORP (JP) | 2006-11-08 | — | — | EP | claimed |
| US-20030171359-A1 | Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-11 | — | — | US | claimed |
| US-5731128-A | ELASTICITY, HARDNESS, ELONGATION; WATER DEVELOPABILITY | NIPPON PAINT CO., LTD. (JP) | 1998-03-24 | — | — | US | claimed |
| US-4046762-A | CENTRAL NERVOUS SYSTEM INHIBITORS | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-09-06 | — | — | US | claimed |
| US-20240052109-A1 | POLYSILOXANE VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2024-02-15 | — | — | US | disclosed |
| EP-2088468-B1 | Method of preparing lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| CN-104125962-A | Tetracyclic anthraquinone derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2014-10-29 | — | — | CN | disclosed |
| US-8420630-B2 | Pyrimidine derivatives | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2013-04-16 | — | — | US | disclosed |
| EP-2098545-B1 | COMPOSITION FOR OIL-RESISTANT WEATHER-RESISTANT RUBBER, AND RUBBER MOLDED BODY | JSR CORP (JP) | 2012-10-10 | — | — | EP | disclosed |
| EP-0513493-A1 | Photosensitive resin composition | Nippon Paint Co., Ltd. (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-5143819-A | Aqueous developing, photocurable composition, photosensitive articles having layers made therefrom and method of improving those articles | W. R. GRACE & CO.-CONN. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5073477-A | Conjugated diene homo and copolymers, unsaturated amine, unsat urated monomer, plate with good strength that can be developed in water | NIPPON PAINT CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0261910-A2 | Water-developable photosensitive plate and its production | Nippon Paint Co., Ltd. (JP) | 1988-03-30 | — | — | EP | disclosed |
| WO-1988002135-A1 | WATER-DEVELOPABLE PHOTOSENSITIVE PLATE AND ITS PRODUCTION | NAPP SYSTEMS (USA), INC. (US) | 1988-03-24 | — | — | WO | disclosed |
| US-4046762-A | CENTRAL NERVOUS SYSTEM INHIBITORS | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171359-A1 | Suitable for treatment of illnesses characterised by excessive or abnormal cell proliferation; viral, bacterial, fungal and/or parasitic infections, skin diseases, bone diseases, cardiovascular diseases | COL1A1, MKI67, INSR | MEN1 591/4885POLB 500/4885KMT2A 3941/4885 |
| US-20100152167-A1 | PYRIMIDINE DERIVATIVES | TYMP, TYMS, DPYD | MEN1 3444/4885POLB 76/4885KMT2A 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.