Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16439861 | 0.96 | LMNA (0.41) | TGFBR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16439982 | 0.94 | LMNA (0.40) | TGFBR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16439872 | 0.94 | LMNA (0.40) | TGFBR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16439957 | 0.94 | LMNA (0.40) | TGFBR1LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16340697 | 0.92 | LMNA (0.41) | TGFBR1LMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2790674 | 0.92 | LMNA (0.41) | TGFBR1LMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2797132 | 0.92 | LMNA (0.41) | TGFBR1LMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2790675 | 0.92 | LMNA (0.41) | TGFBR1LMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL16439877 | 0.92 | TGFBR1 (0.41) | TGFBR1LMNAHCKFLT3MME | |
| SCHEMBL16439931 | 0.82 | LMNA (0.40) | LMNAALDH1A1SMN1; SMN2EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044114-A1 | ACID GAS ABSORBENT, ACID GAS REMOVAL METHOD, AND ACID GAS REMOVAL DEVICE | KABUSHIKI KAISHA TOSHIBA (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2835170-A1 | Acid gas absorbent, acid gas removal method, and acid gas removal device | Kabushiki Kaisha Toshiba (JP) | 2015-02-11 | — | — | EP | disclosed |