SCHEMBL16440797

SCHEMBL16440797

O=P(c1ccccc1)(c1ccccc1)c1ccc2oc3ccc(-c4ccncc4)cc3c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.40
PDE3A Q14432 2/20 0.40
MKNK1 Q9BUB5 1/20 0.40
PIK3CA P42336 1/20 0.40
PLA2G2A P14555 2/20 0.39
PLA2G4A P47712 2/20 0.39
CYP19A1 P11511 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ATAD2 Q6PL18 1/20 0.38
NOTUM Q6P988 1/20 0.38
DYRK1A Q13627 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24470251 0.91 PLA2G2A (0.45) PLA2G2APLA2G4ANPC1RAB9AKDM4E
SCHEMBL16440674 0.91 PLA2G2A (0.37) PDE3BPDE3AMKNK1PIK3CAPLA2G2A
SCHEMBL16440776 0.90 PLA2G2A (0.47) PLA2G2APLA2G4ARAB9AKDM4ELMNA
SCHEMBL16440679 0.90 PLA2G2A (0.47) PLA2G2APLA2G4ARAB9AKDM4ELMNA
SCHEMBL16440643 0.90 ROCK2 (0.40) PLA2G2APLA2G4ANPC1RAB9AKDM4E
SCHEMBL16440646 0.87 PLA2G2A (0.48) PLA2G2APLA2G4ACYP19A1NPC1RAB9A
SCHEMBL15855413 0.87 PLA2G2A (0.46) PLA2G2APLA2G4ARAB9AKDM4EALDH1A1
SCHEMBL16440658 0.87 PLA2G2A (0.48) PLA2G2APLA2G4ACYP19A1NPC1RAB9A
SCHEMBL16440783 0.87 PLA2G2A (0.45) PLA2G2APLA2G4ARAB9AKDM4EALDH1A1
SCHEMBL16440781 0.87 PLA2G2A (0.46) PLA2G2APLA2G4ARAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed