SCHEMBL1644210

SCHEMBL1644210

FC(F)(F)c1ccc2ccccc2c1[S]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
GLA P06280 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
ATM Q13315 1/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPRT1 P00492 1/20 0.41
ULK1 O75385 1/20 0.40
KCNJ11 Q14654 5/20 0.38
ABCC9 O60706 2/20 0.38
ABCC8 Q09428 2/20 0.38
KCNJ8 Q15842 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529007 0.79 HSD17B10 (0.44) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL2513921 0.77 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL17385581 0.75 HSD17B10 (0.44) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL1645664 0.75 ALDH1A1 (0.44) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL4076480 0.75 HSD17B10 (0.68) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL9435264 0.75 CYP2A6 (0.54) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL7304753 0.75 HSD17B10 (0.59) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL5249435 0.75 TSHR (0.54) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL5249429 0.75 HSD17B10 (0.49) HSD17B10ALDH1A1KDM4EHPGDMEN1
SCHEMBL1161290 0.73 KDM4E (0.53) HSD17B10ALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8467018-B2 Color filter and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2013-06-18 US disclosed
US-20110149216-A1 Color filter, coloring composition for color filter and liquid crystal display device TOPPAN PRINTING CO., LTD (JP) 2011-06-23 US disclosed
US-7948583-B2 Color filter, coloring composition for color filter and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-05-24 US disclosed
US-20110096274-A1 Color filter and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-04-28 US disclosed
US-20090284697-A1 Color filter and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2009-11-19 US disclosed
US-20080180611-A1 Color filter, coloring composition for color filter and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2008-07-31 US disclosed