SCHEMBL1644280

SCHEMBL1644280

c1csc(-c2sc(-c3cccs3)c3nc(-c4ccsc4)c(-c4ccsc4)nc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
DHFR P00374 1/20 0.41
HSD17B10 Q99714 2/20 0.40
NPC1 O15118 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
FYN P06241 1/20 0.39
ALDH1A1 P00352 3/20 0.38
ADORA2A P29274 2/20 0.38
CDK5 Q00535 2/20 0.38
CDK5R1 Q15078 2/20 0.38
ADORA1 P30542 1/20 0.38
KDM4E B2RXH2 4/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1198942 0.82 MEN1 (0.51) MEN1KMT2ADHFRCYP1A2CYP3A4
SCHEMBL12886530 0.78 MAPT (0.40) HSD17B10NPC1ALDH1A1ADORA2ACDK5
SCHEMBL7697735 0.76 RPS6KB2 (0.41) MEN1KMT2ADHFRFYNALDH1A1
SCHEMBL14039659 0.75 MAPK14 (0.47) MEN1KMT2ADHFRNPC1ALDH1A1
SCHEMBL19223687 0.74 MEN1 (0.43) MEN1KMT2ADHFRHSD17B10NPC1
SCHEMBL769338 0.73 CYP2A6 (0.50) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL14351350 0.73 MEN1 (0.51) MEN1KMT2ADHFRHSD17B10NPC1
SCHEMBL7699647 0.73 RPS6KB2 (0.73) MEN1KMT2AHSD17B10NPC1FYN
SCHEMBL12902813 0.72 MEN1 (0.51) MEN1KMT2ADHFRHSD17B10NPC1
SCHEMBL22734784 0.70 FYN (0.40) MEN1KMT2AHSD17B10NPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111240118-B Electrochromic device with three-electrode structure and preparation method thereof 浙江工业大学 2023-07-14 CN claimed
US-20230418125-A9 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2023-12-28 US disclosed
CN-111240118-B Electrochromic device with three-electrode structure and preparation method thereof 浙江工业大学 2023-07-14 CN disclosed
US-20220260882-A1 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2022-08-18 US disclosed
US-10948796-B2 Electrochromic materials, devices and applications of the same CHROMERA, INC 2021-03-16 US disclosed
US-20160091767-A1 Novel Electrochromic Materials, Devices And Applications Of The Same CHROMERA, INC. (US) 2016-03-31 US disclosed
US-9030724-B2 Flexible and printable electrooptic devices CHROMERA, INC. (US) 2015-05-12 US disclosed
US-20110096388-A1 Flexible and printable electrooptic devices AJJER LLC (US) 2011-04-28 US disclosed
WO-2010003138-A1 NOVEL ELECTROCHROMIC MATERIALS, DEVICES AND APPLICATIONS OF THE SAME AJJER LLC (US) 2010-01-07 WO disclosed
WO-2009126118-A1 UNIQUE PROCESSABLE GREEN POLYMER WITH A TRANSMISSIVE OXIDIZED STATE FOR REALIZATION OF COMMERICAL RGB BASED ELECTROCHROMIC DEVICE APPLICATIONS TOPPARE LEVENT KAMIL (TR) 2009-10-15 WO disclosed