SCHEMBL769338

SCHEMBL769338

c1csc(-c2ccsc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.50
CYP2B6 P20813 3/20 0.50
CYP2E1 P05181 2/20 0.50
CYP3A4 P08684 3/20 0.47
CYP2C9 P11712 3/20 0.47
LTA4H P09960 1/20 0.47
FYN P06241 1/20 0.46
KCNH2 Q12809 1/20 0.45
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP17A1 P05093 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
NPC1 O15118 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22734795 0.88 KCNH2 (0.42) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL5477270 0.86 CYP2A6 (0.69) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL22734785 0.86 DPP4 (0.49) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL22734809 0.81 CYP2A6 (0.42) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL22734768 0.80 CYP2A6 (0.45) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL22734784 0.78 FYN (0.40) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL22734794 0.78 FYN (0.40) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL1464252 0.76
SCHEMBL338810 0.76 LTA4H (0.70) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL13857515 0.74 FYN (0.37) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US claimed
WO-2006001719-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2006-01-05 WO claimed
EP-4494189-A1 A TRANSFERRABLE PHOTOVOLTAIC DEVICE Commonwealth Scientific and Industrial Research Organisation (AU) 2025-01-22 EP disclosed
US-12202954-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-21 US disclosed
US-20230418125-A9 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2023-12-28 US disclosed
WO-2023191908-A2 PEROVSKITES ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2023-10-05 WO disclosed
WO-2023173171-A1 A TRANSFERRABLE PHOTOVOLTAIC DEVICE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-09-21 WO disclosed
CN-116284083-A Novel pyrrole-containing condensed ring conjugated compound and application thereof in medicine and material field 上海先辉医药科技有限公司 2023-06-23 CN disclosed
US-20230114853-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER MOLDED PRODUCT SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-04-13 US disclosed
CN-112724127-B Five-membered heterocyclic oxocarboxylic acid compound and medical application thereof 中国科学院上海药物研究所 2023-02-17 CN disclosed
US-20220260882-A1 Novel Electrochromic Materials, Devices And Applications Of The Same AGRAWAL ANOOP (US) 2022-08-18 US disclosed
EP-0390850-A1 ANTIFUNGAL CARBINOLS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1990-10-10 EP disclosed
US-4952232-A Antifungal carbinols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-28 US disclosed
WO-1990008145-A1 ANTI-INFLAMMATORY 1-HETEROARYL-3-ACYL-2-OXINDOLES PFIZER INC. (US) 1990-07-26 WO disclosed
EP-0332704-A1 PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM NIPPON SODA CO., LTD. (JP) 1989-09-20 EP disclosed
WO-1989005581-A1 ANTIFUNGAL CARBINOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-06-29 WO disclosed
US-4723988-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-09 US disclosed
CN-87101917-A Has the active novel sulfurized compound of antifungal 1988-01-06 CN disclosed
US-4684393-A PLATN GROWTH REGULATORS E. I. DUPONT DE NEMOURS AND COMPANY (US) 1987-08-04 US disclosed
EP-0165753-A2 Herbicidal thiophenesulfonamides and pyridinesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed