Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 11/20 | 0.73 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692865 | 0.87 | PDGFRB (0.53) | RPS6KB2PDGFRBPDGFRANPC1LMNA | |
| SCHEMBL7692571 | 0.86 | RPS6KB2 (1.00) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL7697735 | 0.76 | RPS6KB2 (0.41) | RPS6KB2RAB9ALMNAGLAKDM4E | |
| SCHEMBL7696744 | 0.75 | RPS6KB2 (0.77) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL7696272 | 0.75 | RPS6KB2 (0.77) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL1086146 | 0.73 | RPS6KB2 (0.63) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL7692004 | 0.73 | RPS6KB2 (0.68) | RPS6KB2SRPK1PDGFRBNPC1RAB9A | |
| SCHEMBL31393470 | 0.73 | RPS6KB2 (0.74) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL16027135 | 0.73 | RPS6KB2 (0.74) | RPS6KB2SRPK1NPC1RAB9AATM | |
| SCHEMBL1644280 | 0.73 | MEN1 (0.47) | RPS6KB2NPC1RAB9AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |