Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445205 | 1.00 | HCAR3 (0.52) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7183022 | 0.89 | HCAR3 (0.52) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7182001 | 0.89 | HCAR3 (0.52) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7181998 | 0.89 | HCAR3 (0.52) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL8248585 | 0.86 | HCAR3 (0.59) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7185961 | 0.83 | HCAR3 (0.56) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7179403 | 0.83 | HCAR3 (0.53) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7185959 | 0.83 | HCAR3 (0.56) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL7179398 | 0.83 | HCAR3 (0.53) | HCAR3KMT2AMEN1L3MBTL1KAT2B | |
| SCHEMBL17739749 | 0.82 | HCAR3 (0.60) | HCAR3KMT2AMEN1L3MBTL1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | TNKS1BP1, TNKS, TBKBP1 | HCAR3 3841/4885KMT2A 2435/4885MEN1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.