Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023859 | 0.83 | LMNA (0.51) | EGFRERBB2CA2 | |
| SCHEMBL10405410 | 0.82 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL23733121 | 0.81 | HDAC2 (0.59) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL21887555 | 0.81 | PDE4B (0.46) | EGFRERBB2CXCL8ALDH1A1CNR2 | |
| SCHEMBL17127746 | 0.81 | EGFR (0.68) | MEN1KMT2AEGFRERBB2 | |
| SCHEMBL16905382 | 0.81 | EGFR (0.53) | MEN1KMT2AEGFRERBB2ALDH1A1 | |
| SCHEMBL27796626 | 0.81 | CA1 (0.57) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL13946581 | 0.79 | MEN1 (0.50) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL7697158 | 0.79 | EGFR (0.67) | MEN1KMT2AEPHX2EGFRERBB2 | |
| Phenylacetic Acid SCHEMBL23925805 | 0.78 | AKR1B1 (0.74) | MEN1KMT2AHDAC8HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230359119-A1 | RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| WO-2015019347-A1 | GIRK AS A THERAPEUTIC TARGET OF IMMUNE DISORDERS AND A MARKER OF B CELL SUBTYPES | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2015-02-12 | — | — | WO | disclosed |
| CN-1318541-A | Sulfonyl-containing pyrrolidone compound and preparation method and pharmaceutical application thereof | INST OF PHARMACOLOGY CHINESE A (CN) | 2001-10-24 | — | — | CN | disclosed |