SCHEMBL23733121

SCHEMBL23733121

CS(=O)(=O)NC(=O)CCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
HDAC1 Q13547 3/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 1/20 0.56
ALDH1A1 P00352 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NR4A2 P43354 1/20 0.53
KDM4E B2RXH2 1/20 0.53
RECQL P46063 1/20 0.53
KEAP1 Q14145 1/20 0.52
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
TSHR P16473 2/20 0.51
PLA2G10 O15496 1/20 0.51
HDAC3 O15379 1/20 0.50
P2RX7 Q99572 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11803107 0.85 HDAC2 (0.63) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL4572811 0.83 PLA2G10 (0.44) HDAC6HDAC1ALDH1A1NR4A2RECQL
SCHEMBL17506960 0.82 HDAC2 (0.59) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL16446138 0.81 MEN1 (0.57) HDAC8HDAC6ALDH1A1HPGDMEN1
SCHEMBL23732466 0.81 HDAC2 (0.54) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL27323350 0.81 MEN1 (0.64) HDAC2HDAC8HDAC6HDAC1MAPT
Phenyl Propionic Acid SCHEMBL27738109 0.79 KEAP1 (0.76) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL353132 0.77 HDAC2 (0.68) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL20597404 0.77 HDAC2 (0.73) HDAC2HDAC8HDAC6HDAC1MAPT
SCHEMBL28189350 0.76 PRMT1 (0.63) HDAC2HDAC8HDAC6HDAC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
WO-2021155004-A1 STRAD-BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 WO disclosed