SCHEMBL1644706

SCHEMBL1644706

c1ccc(C2(c3ccc(Nc4cccc5ccccc45)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.58
▸ HPGD P15428 2/20 0.58
▸ ATM Q13315 2/20 0.58
▸ TP53 P04637 1/20 0.58
▸ CYP3A4 P08684 1/20 0.58
▸ ALOX15 P16050 1/20 0.58
▸ TSHR P16473 1/20 0.58
▸ CDC25B P30305 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ RAB9A P51151 2/20 0.49
▸ MEN1 O00255 5/20 0.46
▸ KMT2A Q03164 5/20 0.46
▸ MAPT P10636 4/20 0.46
▸ KDM4E B2RXH2 4/20 0.46
▸ GAA P10253 2/20 0.46
▸ GLA P06280 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ FADS1 O60427 1/20 0.43
▸ POLB P06746 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15138641 0.91 CDC25B (0.50) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL31027167 0.91 CDC25B (0.50) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL20885275 0.89 CDC25B (0.55) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL24883059 0.85 CYP3A4 (0.49) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL25569099 0.84 MEN1 (0.42) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL25850849 0.84 ALDH1A1 (0.43) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL25034288 0.83 CYP3A4 (0.46) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL22662364 0.83 CDC25B (0.41) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL20871520 0.82 MAPT (0.49) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL21214788 0.82 ALDH1A1 (0.43) ALDH1A1HPGDATMTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230009845-A1 ORGANIC ELECTRIC ELEMENT COMPRISING A PLURALITY OF EMISSION-AUXILIARY LAYERS AND ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2023-01-12 — — US disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 — — US disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 — — US disclosed
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-13 — — US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 — — US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 — — US disclosed
US-9553273-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-24 — — US disclosed
CN-103102277-B Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-22 — — CN disclosed
US-20140131697-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-15 — — US disclosed
US-20140131697-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-15 — — US disclosed
US-8642190-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-8642190-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
EP-2314565-B1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2013-07-24 — — EP disclosed
EP-2314565-B1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2013-07-24 — — EP disclosed
CN-103102277-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-05-15 — — CN disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 — — US disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 — — US disclosed
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-28 — — US disclosed
EP-2314565-A1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-27 — — EP disclosed
EP-2314565-A1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170104157-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, LEF1 ALDH1A1 129/4885HPGD 3787/4885ATM 2945/4885
US-20110095678-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, LEF1 ALDH1A1 129/4885HPGD 3787/4885ATM 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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