Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455608 | 0.87 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CTSSNPC1 | |
| SCHEMBL26638908 | 0.81 | DHODH (0.48) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL30638272 | 0.81 | DHODH (0.48) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL16833488 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2CTSSNPC1 | |
| SCHEMBL16846266 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2CTSSNPC1 | |
| SCHEMBL12525326 | 0.81 | AAK1 (0.50) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL16846299 | 0.78 | AAK1 (0.48) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL20803487 | 0.78 | AAK1 (0.48) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL3484534 | 0.78 | SMN1; SMN2 (0.47) | MEN1KMT2AMGLLSMN1; SMN2L3MBTL1 | |
| SCHEMBL567578 | 0.77 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CTSSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242145-B2 | Cyclic diaryl ether compounds as antagonists of prostaglandin D2 receptors | PANMIRA PHARMACEUTICALS, LLC (US) | 2012-08-14 | — | — | US | disclosed |
| US-20110098302-A1 | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098302-A1 | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | PTGDR, PTGDR2, PTGER1 | MEN1 4770/4885KMT2A 4201/4885MGLL 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.