Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970736 | 0.88 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8282485 | 0.87 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL12998272 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2187660 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28844314 | 0.86 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3560316 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL847723 | 0.86 | KMT2A (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2187792 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16533483 | 0.86 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3843818 | 0.85 | OPRM1 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573511-B | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-114703144-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114621222-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220009918-A1 | Chemical Compounds | GLAXOSMITHKLINE IP DEV LTD (GB) | 2022-01-13 | — | — | US | disclosed |
| CN-110573511-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-20170066782-A1 | DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE | NEKTAR THERAPEUTICS | 2017-03-09 | — | — | US | disclosed |
| US-20170066782-A1 | DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE | NEKTAR THERAPEUTICS | 2017-03-09 | — | — | US | disclosed |
| US-9248117-B2 | Substituted N,N-dihaloamines as antimicrobials | NOVABAY PHARMACEUTICALS, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| EP-2444395-B1 | SUBSTITUTED ISOQUINOLINE DERIVATIVE | WESTERN THERAPEUTICS INST INC D (JP) | 2016-01-06 | — | — | EP | disclosed |
| EP-2444395-B1 | SUBSTITUTED ISOQUINOLINE DERIVATIVE | WESTERN THERAPEUTICS INST INC D (JP) | 2016-01-06 | — | — | EP | disclosed |
| EP-0259835-B1 | PYRIDAZINONE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4843072-A | Antihypertensive pyridazinone aminoisopropanol derivatives | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0259835-A2 | Pyridazinone derivatives | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4171452-A | FUNGICIDES | INTERX RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4132805-A | Novel soft N-chloroamino alcohol derivatives exhibiting antibacterial activity | INTERX RESEARCH CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4115588-A | Antibacterial novel soft n-chloroamino alcohol derivatives | INTERX RESEARCH CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4092420-A | Novel soft N-chloroamino alcohol derivatives exhibiting antibacterial activity | INTERX RESEARCH CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4036843-A | ANTIBACTERIAL | INTERX RESEARCH CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009918-A1 | Chemical Compounds | HPGDS, PTGS1, PTGER1 | MEN1 4055/4885KMT2A 3678/4885SMN1; SMN2 281/4885 |
| US-20170066782-A1 | DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE | KCNJ2, TRPC5, RYR2 | MEN1 1531/4885KMT2A 464/4885SMN1; SMN2 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.