SCHEMBL1644827

SCHEMBL1644827

ClCC(Cl)C1C=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.37
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6856381 0.81 HTR6 (0.44) HTR2AHTR6SIGMAR1
SCHEMBL11593978 0.81 HTR2A (0.34) HTR2AHTR6SIGMAR1
SCHEMBL6752383 0.80 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL9459873 0.79 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL4006405 0.76 SIGMAR1 (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL6684913 0.76 SIGMAR1 (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
Ethylene SCHEMBL4339093 0.76 HTR2A (0.34) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL1535521 0.76 HTR2A (0.34) HTR2AHTR6SIGMAR1
SCHEMBL21044941 0.74 HTR2A (0.37) HTR2AHTR6
SCHEMBL7927919 0.73 HTR2A (0.35) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225757-B2 Barrier laminate with excellent barrier properties against moisture and gas and method of manufacturing same HANSOL PAPER CO., LTD. (KR) 2022-01-18 US claimed
EP-3922770-A1 BARRIER LAMINATE WITH EXCELLENT BARRIER PROPERTIES AGAINST MOISTURE AND GAS AND METHOD OF MANUFACTURING SAME Hansol Paper Co., Ltd. (KR) 2021-12-15 EP claimed
US-20200291580-A1 BARRIER LAMINATE WITH EXCELLENT BARRIER PROPERTIES AGAINST MOISTURE AND GAS AND METHOD OF MANUFACTURING SAME HANSOL PAPER CO., LTD. (KR) 2020-09-17 US claimed
EP-3620576-A1 BARRIER LAMINATE HAVING EXCELLENT MOISTURE AND GAS BARRIER PROPERTIES, AND METHOD FOR PRODUCING SAME Hansol Paper Co., Ltd. (KR) 2020-03-11 EP claimed
WO-2010036998-A2 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF ABBOTT LABORATORIES (US) 2010-04-01 WO claimed
EP-1896530-A4 THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS BEAULIEU GROUP LLC (US) 2009-08-26 EP claimed
EP-1896530-A2 THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS Beaulieu Group, LLC (US) 2008-03-12 EP claimed
WO-2006135809-A2 THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS BEAULIEU GROUP, LLC D/B/A BEAULIEU OF AMERICA (US) 2006-12-21 WO claimed
US-20060281851-A1 THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS BRANCH BANKING AND TRUST COMPANY, AS ADMINISTRATIVE AGENT 2006-12-14 US claimed
US-4795475-A Prosthesis utilizing salt-forming oxyacids for bone fixation WALKER MICHAEL M (US) 1989-01-03 US claimed
JP-61078887-A None JP disclosed
JP-11154628-A None JP disclosed
US-11225757-B2 Barrier laminate with excellent barrier properties against moisture and gas and method of manufacturing same HANSOL PAPER CO., LTD. (KR) 2022-01-18 US disclosed
EP-3922770-A1 BARRIER LAMINATE WITH EXCELLENT BARRIER PROPERTIES AGAINST MOISTURE AND GAS AND METHOD OF MANUFACTURING SAME Hansol Paper Co., Ltd. (KR) 2021-12-15 EP disclosed
US-20210252186-A1 AN ADHESIVE LAYERED MATRIX AND USES THEREOF NURAMI MEDICAL LTD. (IL) 2021-08-19 US disclosed
WO-1990001504-A1 MALEIC ANHYDRIDE GRAFT COPOLYMER PRODUCTS HAVING LOW YELLOWNESS INDEX AND PREPARATION THE DOW CHEMICAL COMPANY (US) 1990-02-22 WO disclosed
EP-0197179-B1 DISPOSABLE RESERVOIR CASSETTE Becton Dickinson and Company (US) 1988-11-09 EP disclosed
JP-S6178887-A HEAT-PEELABLE SELF-ADHESIVE SHEET SHINKO KAGAKU KOGYO KK 1986-04-22 JP disclosed
EP-0005866-B1 AN OXYGENATOR TERUMO CORPORATION (JP) 1981-08-26 EP disclosed
US-4147687-A Formed objects of coal flyash and methods of making the same DONNELL HUGH T O 1979-04-03 US disclosed