Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524013 | 0.81 | PIM1 (0.54) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL28105832 | 0.79 | MAOB (0.49) | CYP19A1MAOAMAOBHDAC6 | |
| SCHEMBL16448790 | 0.78 | HSD17B3 (0.60) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL742927 | 0.76 | PIM1 (0.55) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL28818101 | 0.75 | PIM1 (0.54) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL205825 | 0.74 | ALOX15 (0.69) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL3927927 | 0.74 | KMT2A (0.49) | KMT2APOLBMEN1KDM4EALDH1A1 | |
| SCHEMBL743339 | 0.73 | PIM1 (0.52) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL3133971 | 0.73 | POLB (0.56) | PIM1KMT2APOLBMEN1GAA | |
| SCHEMBL437460 | 0.73 | GAA (0.67) | PIM1KMT2APOLBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952185-B2 | Production method of optically active dihydrobenzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |