Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442305 | 0.89 | NR1I2 (0.35) | NR1I2HIF1ALPLLIPGKIF11 | |
| SCHEMBL30640498 | 0.85 | LPL (0.40) | HIF1ALPLLIPGKIF11 | |
| SCHEMBL26185543 | 0.85 | LPL (0.40) | HIF1ALPLLIPGKIF11 | |
| SCHEMBL26621961 | 0.84 | LPL (0.39) | NR1I2HIF1ALPLLIPGKIF11 | |
| SCHEMBL4586623 | 0.84 | LPL (0.33) | HIF1ALPLLIPG | |
| SCHEMBL21777914 | 0.81 | LPL (0.36) | NR1I2HIF1ALPLLIPGKIF11 | |
| SCHEMBL19412199 | 0.79 | NR1I2 (0.39) | NR1I2HIF1ALPLLIPG | |
| SCHEMBL29470104 | 0.79 | NR1I2 (0.39) | NR1I2HIF1ALPLLIPG | |
| SCHEMBL27026509 | 0.79 | HIF1A (0.44) | NR1I2HIF1ALPLLIPG | |
| SCHEMBL1984017 | 0.78 | LPL (0.33) | HIF1ALPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951648-B2 | Diacenaphtho[1,2-b:1′,2′-k]chrysene derivative | CANON KABUSHIKI KAISHA (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8951648-B2 | Diacenaphtho[1,2-b:1′,2′-k]chrysene derivative | CANON KABUSHIKI KAISHA (JP) | 2015-02-10 | — | — | US | disclosed |