SCHEMBL1984017

SCHEMBL1984017

CC(C)(C)c1cc2ccc3ccc(B4OC(C)(C)C(C)(C)O4)c4ccc(c1)c2c34

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
HIF1A Q16665 1/20 0.32
ERBB2 P04626 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14954464 0.92 LPL (0.36) LPLLIPG
SCHEMBL2816050 0.86 LPL (0.38) LPLLIPG
SCHEMBL4586623 0.85 LPL (0.33) LPLLIPGHIF1A
SCHEMBL2226414 0.85 LPL (0.31) LPLLIPGHIF1A
SCHEMBL12390693 0.83
SCHEMBL29851154 0.83 ALDH1A1 (0.44) LPLLIPGERBB2CYP1A2FYN
SCHEMBL224510 0.83 ALDH1A1 (0.44) LPLLIPGERBB2CYP1A2FYN
SCHEMBL14680420 0.82 LPL (0.30) LPLLIPG
SCHEMBL24608926 0.80 LPL (0.30) LPLLIPG
SCHEMBL2403716 0.80 LPL (0.44) LPLLIPGHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9988403-B2 Compositions and methods for treating cancer with aberrant lipogenic signaling THOMAS JEFFERSON UNIVERSITY (US) 2018-06-05 US disclosed
US-9988403-B2 Compositions and methods for treating cancer with aberrant lipogenic signaling THOMAS JEFFERSON UNIVERSITY (US) 2018-06-05 US disclosed
US-20180059566-A1 UV-CURABLE LIQUID DEVELOPER, FIXING METHOD, IMAGE FORMING METHOD, AND UV-CURABLE COMPOSITION CANON KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-20180059566-A1 UV-CURABLE LIQUID DEVELOPER, FIXING METHOD, IMAGE FORMING METHOD, AND UV-CURABLE COMPOSITION CANON KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-9812646-B2 Organic compound and organic light-emitting device and display apparatus having the same CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9812646-B2 Organic compound and organic light-emitting device and display apparatus having the same CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9750758-B2 Compositions and methods for treating cancer with aberrant lipogenic signaling THOMAS JEFFERSON UNIVERSITY (US) 2017-09-05 US disclosed
US-9750758-B2 Compositions and methods for treating cancer with aberrant lipogenic signaling THOMAS JEFFERSON UNIVERSITY (US) 2017-09-05 US disclosed
EP-2903958-B1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS HAVING THE SAME CANON KK (JP) 2017-08-30 EP disclosed
US-20170166593-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER WITH ABERRANT LIPOGENIC SIGNALING THOMAS JEFFERSON UNIVERSITY (US) 2017-06-15 US disclosed
US-20080224603-A1 NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-09-18 US disclosed
US-20080224603-A1 NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-09-18 US disclosed
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-06-05 US disclosed
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-06-05 US disclosed
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-05-22 US disclosed
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-05-22 US disclosed
US-7365198-B2 Silyl compound, light emitting material, and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-04-29 US disclosed
WO-2008015945-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-02-07 WO disclosed
WO-2007123256-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2007-11-01 WO disclosed
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080224603-A1 NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND AHR, CRY1, NR2E3 LPL 2237/4885LIPG 3815/4885HIF1A 1246/4885
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME OXA1L, CYP2C19, PPOX LPL 2695/4885LIPG 3192/4885HIF1A 4090/4885
US-20170166593-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER WITH ABERRANT LIPOGENIC SIGNALING SREBF1, SREBF2, OSBP LPL 56/4885LIPG 77/4885HIF1A 185/4885
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE AHR, CYP1A1, ARNT LPL 3508/4885LIPG 4480/4885HIF1A 2123/4885
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LAS1L, CCNL2, EML4 LPL 1558/4885LIPG 2825/4885HIF1A 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.