SCHEMBL16448982

SCHEMBL16448982

Cc1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5ccc(-c6ccc(C)s6)s5)cc4)c4ccccc34)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.40
CYP2A6 P11509 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 4/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
ENPP1 P22413 2/20 0.33
NCK1 P16333 1/20 0.33
BACE1 P56817 1/20 0.33
IKBKB O14920 1/20 0.33
MAOA P21397 1/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14505913 0.92 CYP2A6 (0.41) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL14505906 0.90 CYP2A6 (0.42) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL14505909 0.88 HSD17B1 (0.41) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL14505924 0.86 HSD17B1 (0.41) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL14505903 0.86 HSD17B1 (0.41) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL18099811 0.82 PGR (0.46) PGRCYP2A6TDP1CYP1A2ALDH1A1
SCHEMBL2608308 0.81 PGR (0.55) PGRCYP2A6TDP1CYP1A2ALDH1A1
SCHEMBL12571791 0.80 CYP1A1 (0.38) CYP1A2SMN1; SMN2HSD17B1HSD17B2IKBKB
SCHEMBL11954106 0.80 ENPP1 (0.39) CYP2A6TDP1SMN1; SMN2CYP3A4HSD17B1
SCHEMBL14505876 0.79 HSD17B1 (0.49) CYP2A6TDP1CYP1A2SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8951831-B2 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same LG CHEM, LTD. (KR) 2015-02-10 US disclosed
US-8951831-B2 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same LG CHEM, LTD. (KR) 2015-02-10 US disclosed