Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10136994 | 0.90 | KDM4E (0.44) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL13996862 | 0.86 | KDM4E (0.59) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL12530151 | 0.85 | KDM4E (0.45) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10168658 | 0.78 | KDM4E (0.51) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL14950829 | 0.77 | KDM4E (0.58) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL2737171 | 0.77 | KDM4E (0.33) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL12530089 | 0.73 | ENPP2 (0.42) | KDM4ERAB9AALDH1A1ACHEBCHE | |
| SCHEMBL16449242 | 0.72 | KDM4E (0.35) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL12530183 | 0.71 | ENPP2 (0.31) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL5953945 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |