⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737171 | 0.90 | KDM4E (0.33) | — | |
| SCHEMBL12530183 | 0.85 | ENPP2 (0.31) | — | |
| SCHEMBL10136994 | 0.76 | KDM4E (0.44) | — | |
| SCHEMBL5953337 | 0.72 | RAB9A (0.38) | — | |
| SCHEMBL19194662 | 0.69 | — | — | |
| SCHEMBL16449244 | 0.68 | KDM4E (0.44) | — | |
| SCHEMBL10168658 | 0.67 | KDM4E (0.51) | — | |
| SCHEMBL10137077 | 0.67 | — | — | |
| SCHEMBL14950829 | 0.64 | KDM4E (0.58) | — | |
| SCHEMBL2737207 | 0.63 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-8983565-B2 | Optical determination of pH and glucose | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8979790-B2 | Use of an equilibrium sensor to monitor glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140350364-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | CITIBANK, N.A. | 2014-11-27 | — | — | US | disclosed |
| US-20140058225-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | GLUMETRICS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140018646-A1 | USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL | GLUMETRICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20130287631-A1 | MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION | MEDTRONIC MINIMED, INC. | 2013-10-31 | — | — | US | disclosed |
| US-8535262-B2 | Use of an equilibrium intravascular sensor to achieve tight glycemic control | GLUMETRICS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8473222-B2 | Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction | GLUMETRICS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120116191-A1 | USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL | GLUMETRICS, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110224516-A1 | MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION | GLUMETRICS, INC. (US) | 2011-09-15 | — | — | US | disclosed |